Journal article
Palwasha Abbasi, A. R. Memon, Sadia Abbasi, Sadia Kazi, S. Siddiqui
The Professional Medical Journal, 2015
The Professional Medical Journal, 2015
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APA
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Abbasi, P., Memon, A. R., Abbasi, S., Kazi, S., & Siddiqui, S. (2015). HYPERGLYCEMIA. The Professional Medical Journal.
Chicago/Turabian
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Abbasi, Palwasha, A. R. Memon, Sadia Abbasi, Sadia Kazi, and S. Siddiqui. “HYPERGLYCEMIA.” The Professional Medical Journal (2015).
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Abbasi, Palwasha, et al. “HYPERGLYCEMIA.” The Professional Medical Journal, 2015.
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@article{palwasha2015a,
title = {HYPERGLYCEMIA},
year = {2015},
journal = {The Professional Medical Journal},
author = {Abbasi, Palwasha and Memon, A. R. and Abbasi, Sadia and Kazi, Sadia and Siddiqui, S.}
}
Abstract
Objectives: To investigate blood glucose regulaitng effects of CatharanthusRoseus (C.roseus) and Nigella sativa (N.sativa) in alloxan induced diabetic rats. Study Design:Experimental study. Place and Duration: Animal house Isra University Hyderabad. From Aprilto Novermber 2013. Methodology: 50 male rats were housed at normal température, 12 hourdark - light cycle with free access to chow and water. A single intraperitoneal bolus of alloxan(120 mg/kg) was given to induce diabetes mellitus. Glimepiride, C. roseus and N. Sativa wereadministered at doses of 0.1 mg/kg, 125 mg/kg and 50 g/kg respectively. Data was analyzed onSPSS version 21.0. Significant P - value was defined at ≤ 0.05. Results: C.roseus ad N.sativashowed blood glucose lowering potential but the effect was less when compared to glimepiride(P = 0.001). However, C. roseus was more effective compared to N.sativa (P = 0.001) inreducing blood glucose. Findings suggest that both C. roseus and N. sativa possess glucoseregulating potential. Conclusion: It is concluded that the C. roseus and N. sativa exert bloodglucose regulating effects in alloxan induced diabetic rat model.